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Good syndrome with cytomegalovirus hepatitis: successful resection of Thymoma: a case report

BACKGROUND: Good syndrome is a rare condition, manifesting as immunodeficiency due to hypogammaglobulinemia associated with thymoma. Herein, we present a patient with Good syndrome whose thymoma was resected after treatment of cytomegalovirus hepatitis. CASE PRESENTATION: The patient was a 45-year-o...

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Autores principales: Isobe, Sho, Sano, Atsushi, Otsuka, Hajime, Azuma, Yoko, Koezuka, Satoshi, Makino, Takashi, Sakai, Takashi, Ito, Takafumi, Maeda, Tadashi, Ejima, Kozue, Homma, Sakae, Iyoda, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296951/
https://www.ncbi.nlm.nih.gov/pubmed/32539831
http://dx.doi.org/10.1186/s13019-020-01187-y
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author Isobe, Sho
Sano, Atsushi
Otsuka, Hajime
Azuma, Yoko
Koezuka, Satoshi
Makino, Takashi
Sakai, Takashi
Ito, Takafumi
Maeda, Tadashi
Ejima, Kozue
Homma, Sakae
Iyoda, Akira
author_facet Isobe, Sho
Sano, Atsushi
Otsuka, Hajime
Azuma, Yoko
Koezuka, Satoshi
Makino, Takashi
Sakai, Takashi
Ito, Takafumi
Maeda, Tadashi
Ejima, Kozue
Homma, Sakae
Iyoda, Akira
author_sort Isobe, Sho
collection PubMed
description BACKGROUND: Good syndrome is a rare condition, manifesting as immunodeficiency due to hypogammaglobulinemia associated with thymoma. Herein, we present a patient with Good syndrome whose thymoma was resected after treatment of cytomegalovirus hepatitis. CASE PRESENTATION: The patient was a 45-year-old woman presenting with fever, cough, and nasal discharge, and was diagnosed with thymoma and hypogammaglobulinemia. She subsequently developed cytomegalovirus hepatitis that was treated by immunoglobulin. After resolution of the hepatitis, she underwent thymectomy through a left anterior thoracotomy. Her postoperative course was uneventful, and while receiving ongoing immunoglobulin therapy, she has been doing well without signs of infection. CONCLUSIONS: Management of infections is important for patients with Good syndrome. To minimize the risk of perioperative infection, we should take care while planning the surgical approach and procedure.
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spelling pubmed-72969512020-06-16 Good syndrome with cytomegalovirus hepatitis: successful resection of Thymoma: a case report Isobe, Sho Sano, Atsushi Otsuka, Hajime Azuma, Yoko Koezuka, Satoshi Makino, Takashi Sakai, Takashi Ito, Takafumi Maeda, Tadashi Ejima, Kozue Homma, Sakae Iyoda, Akira J Cardiothorac Surg Case Report BACKGROUND: Good syndrome is a rare condition, manifesting as immunodeficiency due to hypogammaglobulinemia associated with thymoma. Herein, we present a patient with Good syndrome whose thymoma was resected after treatment of cytomegalovirus hepatitis. CASE PRESENTATION: The patient was a 45-year-old woman presenting with fever, cough, and nasal discharge, and was diagnosed with thymoma and hypogammaglobulinemia. She subsequently developed cytomegalovirus hepatitis that was treated by immunoglobulin. After resolution of the hepatitis, she underwent thymectomy through a left anterior thoracotomy. Her postoperative course was uneventful, and while receiving ongoing immunoglobulin therapy, she has been doing well without signs of infection. CONCLUSIONS: Management of infections is important for patients with Good syndrome. To minimize the risk of perioperative infection, we should take care while planning the surgical approach and procedure. BioMed Central 2020-06-15 /pmc/articles/PMC7296951/ /pubmed/32539831 http://dx.doi.org/10.1186/s13019-020-01187-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Isobe, Sho
Sano, Atsushi
Otsuka, Hajime
Azuma, Yoko
Koezuka, Satoshi
Makino, Takashi
Sakai, Takashi
Ito, Takafumi
Maeda, Tadashi
Ejima, Kozue
Homma, Sakae
Iyoda, Akira
Good syndrome with cytomegalovirus hepatitis: successful resection of Thymoma: a case report
title Good syndrome with cytomegalovirus hepatitis: successful resection of Thymoma: a case report
title_full Good syndrome with cytomegalovirus hepatitis: successful resection of Thymoma: a case report
title_fullStr Good syndrome with cytomegalovirus hepatitis: successful resection of Thymoma: a case report
title_full_unstemmed Good syndrome with cytomegalovirus hepatitis: successful resection of Thymoma: a case report
title_short Good syndrome with cytomegalovirus hepatitis: successful resection of Thymoma: a case report
title_sort good syndrome with cytomegalovirus hepatitis: successful resection of thymoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296951/
https://www.ncbi.nlm.nih.gov/pubmed/32539831
http://dx.doi.org/10.1186/s13019-020-01187-y
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