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Structure and ligand binding of the ADP-binding domain of the NAD(+) riboswitch
The nadA motif is the first known NAD(+)-dependent riboswitch, comprising two similar tandem bulged stem–loop structures. We have determined the structure of the 5′ domain 1 of the riboswitch. It has three coaxial helical segments, separated by an ACANCCCC bulge and by an internal loop, with a terti...
Autores principales: | Huang, Lin, Wang, Jia, Lilley, David M.J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297122/ https://www.ncbi.nlm.nih.gov/pubmed/32295864 http://dx.doi.org/10.1261/rna.074898.120 |
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