Peli1 signaling blockade attenuates congenital zika syndrome

Zika virus (ZIKV) infects pregnant women and causes devastating congenital zika syndrome (CZS). How the virus is vertically transmitted to the fetus and induces neuronal loss remains unclear. We previously reported that Pellino (Peli)1, an E3 ubiquitin ligase, promotes p38MAPK activation in microgli...

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Detalles Bibliográficos
Autores principales: Luo, Huanle, Li, Guangyu, Wang, Binbin, Tian, Bing, Gao, Junling, Zou, Jing, Shi, Shuizhen, Zhu, Shuang, Peng, Bi-Hung, Adam, Awadalkareem, Martinez, Ariza, Hein, Kimberly, Winkelmann, Evandro R., Mahmoud, Yoseph, Zhou, Xiaofei, Shan, Chao, Rossi, Shannan, Weaver, Scott, Barrett, Alan D. T., Sun, Shao-Cong, Zhang, Wenbo, Shi, Pei-Yong, Wu, Ping, Wang, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297310/
https://www.ncbi.nlm.nih.gov/pubmed/32544190
http://dx.doi.org/10.1371/journal.ppat.1008538

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