Cargando…

An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposons

Insecticide resistance in malaria vectors threatens to reverse recent gains in malaria control. Deciphering patterns of gene flow and resistance evolution in malaria vectors is crucial to improving control strategies and preventing malaria resurgence. A genome-wide survey of Anopheles funestus genet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weedall, Gareth D., Riveron, Jacob M., Hearn, Jack, Irving, Helen, Kamdem, Colince, Fouet, Caroline, White, Bradley J., Wondji, Charles S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297382/ https://www.ncbi.nlm.nih.gov/pubmed/32497040 http://dx.doi.org/10.1371/journal.pgen.1008822

Ejemplares similares

Gene Conversion Explains Elevated Diversity in the Immunity Modulating APL1 Gene of the Malaria Vector Anopheles funestus
por: Hearn, Jack, et al.
Publicado: (2022)

Rise of multiple insecticide resistance in Anopheles funestus in Malawi: a major concern for malaria vector control
por: Riveron, Jacob M., et al.
Publicado: (2015)

Cis-regulatory CYP6P9b P450 variants associated with loss of insecticide-treated bed net efficacy against Anopheles funestus
por: Mugenzi, Leon M. J., et al.
Publicado: (2019)

Multiple insecticide resistance in the major malaria vector Anopheles funestus in southern Ghana: implications for malaria control
por: Riveron, Jacob M., et al.
Publicado: (2016)

Multiple insecticide resistance in an infected population of the malaria vector Anopheles funestus in Benin
por: Djouaka, Rousseau, et al.
Publicado: (2016)

Multi‐omics analysis identifies a CYP9K1 haplotype conferring pyrethroid resistance in the malaria vector Anopheles funestus in East Africa
por: Hearn, Jack, et al.
Publicado: (2022)

Evidence of a multiple insecticide resistance in the malaria vector Anopheles funestus in South West Nigeria
por: Djouaka, Rousseau J., et al.
Publicado: (2016)

Investigating the molecular basis of multiple insecticide resistance in a major malaria vector Anopheles funestus (sensu stricto) from Akaka-Remo, Ogun State, Nigeria
por: Atoyebi, Seun M., et al.
Publicado: (2020)

CYP6P9-Driven Signatures of Selective Sweep of Metabolic Resistance to Pyrethroids in the Malaria Vector Anopheles funestus Reveal Contemporary Barriers to Gene Flow
por: Djuicy, Delia Doreen, et al.
Publicado: (2020)

RNAseq-based gene expression profiling of the Anopheles funestus pyrethroid-resistant strain FUMOZ highlights the predominant role of the duplicated CYP6P9a/b cytochrome P450s
por: Wondji, Charles S, et al.
Publicado: (2021)

Exploring Mechanisms of Multiple Insecticide Resistance in a Population of the Malaria Vector Anopheles funestus in Benin
por: Djouaka, Rousseau, et al.
Publicado: (2011)

Exploring the Mechanisms of Multiple Insecticide Resistance in a Highly Plasmodium-Infected Malaria Vector Anopheles funestus Sensu Stricto from Sahel of Northern Nigeria
por: Ibrahim, Sulaiman S., et al.
Publicado: (2020)

Contrasting Plasmodium infection rates and insecticide susceptibility profiles between the sympatric sibling species Anopheles parensis and Anopheles funestus s.s: a potential challenge for malaria vector control in Uganda
por: Mulamba, Charles, et al.
Publicado: (2014)

Molecular tools for studying the major malaria vector Anopheles funestus: improving the utility of the genome using a comparative poly(A) and Ribo-Zero RNAseq analysis
por: Weedall, Gareth D., et al.
Publicado: (2015)

Escalation of Pyrethroid Resistance in the Malaria Vector Anopheles funestus Induces a Loss of Efficacy of Piperonyl Butoxide–Based Insecticide-Treated Nets in Mozambique
por: Riveron, Jacob M, et al.
Publicado: (2019)

Genome-Wide Transcriptional Analysis and Functional Validation Linked a Cluster of Epsilon Glutathione S-Transferases with Insecticide Resistance in the Major Malaria Vector Anopheles funestus across Africa
por: Kouamo, Mersimine F. M., et al.
Publicado: (2021)

A differential expression of pyrethroid resistance genes in the malaria vector Anopheles funestus across Uganda is associated with patterns of gene flow
por: Sandeu, Maurice Marcel, et al.
Publicado: (2020)

Exploring the impact of glutathione S-transferase (GST)-based metabolic resistance to insecticide on vector competence of Anopheles funestus for Plasmodium falciparum
por: Ndo, Cyrille, et al.
Publicado: (2019)

Multiple Insecticide Resistance in the Malaria Vector Anopheles funestus from Northern Cameroon Is Mediated by Metabolic Resistance Alongside Potential Target Site Insensitivity Mutations
por: Menze, Benjamin D., et al.
Publicado: (2016)

A marker of glutathione S-transferase-mediated resistance to insecticides is associated with higher Plasmodium infection in the African malaria vector Anopheles funestus
por: Tchouakui, Magellan, et al.
Publicado: (2019)

Genomic Footprints of Selective Sweeps from Metabolic Resistance to Pyrethroids in African Malaria Vectors Are Driven by Scale up of Insecticide-Based Vector Control
por: Barnes, Kayla G., et al.
Publicado: (2017)

Genomic insights into adaptive divergence and speciation among malaria vectors of the Anopheles nili group
por: Fouet, Caroline, et al.
Publicado: (2017)

Fitness Costs of the Glutathione S-Transferase Epsilon 2 (L119F-GSTe2) Mediated Metabolic Resistance to Insecticides in the Major African Malaria Vector Anopheles Funestus
por: Tchouakui, Magellan, et al.
Publicado: (2018)

Pyrethroid Resistance in the Major Malaria Vector Anopheles funestus is Exacerbated by Overexpression and Overactivity of the P450 CYP6AA1 Across Africa
por: Ibrahim, Sulaiman S., et al.
Publicado: (2018)

Resistance to clothianidin reduces the efficacy of SumiShield(®) 50WG, a neonicotinoid formulation for indoor residual spraying, against Anopheles gambiae
por: Fouet, Caroline, et al.
Publicado: (2023)

Molecular drivers of insecticide resistance in the Sahelo-Sudanian populations of a major malaria vector Anopheles coluzzii
por: Ibrahim, Sulaiman S., et al.
Publicado: (2023)

Widespread Pyrethroid and DDT Resistance in the Major Malaria Vector Anopheles funestus in East Africa Is Driven by Metabolic Resistance Mechanisms
por: Mulamba, Charles, et al.
Publicado: (2014)

Investigating molecular basis of lambda-cyhalothrin resistance in an Anopheles funestus population from Senegal
por: Samb, Badara, et al.
Publicado: (2016)

Genome-Wide Transcription and Functional Analyses Reveal Heterogeneous Molecular Mechanisms Driving Pyrethroids Resistance in the Major Malaria Vector Anopheles funestus Across Africa
por: Riveron, Jacob M., et al.
Publicado: (2017)

CRISPR-mediated knock-in of transgenes into the malaria vector Anopheles funestus
por: Quinn, Charlotte, et al.
Publicado: (2021)

Molecular basis of permethrin and DDT resistance in an Anopheles funestus population from Benin
por: Tchigossou, Genevieve, et al.
Publicado: (2018)

Investigating knockdown resistance (kdr) mechanism against pyrethroids/DDT in the malaria vector Anopheles funestus across Africa
por: Irving, Helen, et al.
Publicado: (2017)

Functional characterisation of cytochrome P450s involved in insecticide resistance in major malaria vector Anopheles funestus across Africa
por: Wondji, Charles, et al.
Publicado: (2014)

The impact of temperature on insecticide toxicity against the malaria vectors Anopheles arabiensis and Anopheles funestus
por: Glunt, Katey D., et al.
Publicado: (2018)

Multiple insecticide resistance and Plasmodium infection in the principal malaria vectors Anopheles funestus and Anopheles gambiae in a forested locality close to the Yaoundé airport, Cameroon
por: Nkemngo, Francis N., et al.
Publicado: (2020)

Pyrethroid Resistance in an Anopheles funestus Population from Uganda
por: Morgan, John C., et al.
Publicado: (2010)

Pollutants and Insecticides Drive Local Adaptation in African Malaria Mosquitoes
por: Kamdem, Colince, et al.
Publicado: (2017)

Exposure to the insecticide-treated bednet PermaNet 2.0 reduces the longevity of the wild African malaria vector Anopheles funestus but GSTe2-resistant mosquitoes live longer
por: Tchakounte, Ange, et al.
Publicado: (2019)

Mapping the distribution of Anopheles funestus across Benin highlights a sharp contrast of susceptibility to insecticides and infection rate to Plasmodium between southern and northern populations
por: Djouaka, Rousseau, et al.
Publicado: (2017)

Positional cloning of rp2 QTL associates the P450 genes CYP6Z1, CYP6Z3 and CYP6M7 with pyrethroid resistance in the malaria vector Anopheles funestus
por: Irving, H, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qe23a0ugl6hnca8rr0vg18kuki