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A human H1-HBB11-GFP reporter embryonic stem cell line (WAe001-A-2) generated using TALEN-based genome editing

Hemoglobin production during mammalian development is characterized by temporal switches of the genes coding for the α- and β-globin chains. Defects in this controlled process can lead to hemoglobinapathies such as sickle cell disease and β-thalassemia. The ability of human embryonic stem cells (hES...

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Detalles Bibliográficos
Autores principales: Alexeeva, Vera, Aydin, Iraz T., Schaniel, Christoph, Stranahan, Alec W., D’Souza, Sunita L., Bieker, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297435/
https://www.ncbi.nlm.nih.gov/pubmed/32413789
http://dx.doi.org/10.1016/j.scr.2020.101837