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Pharmacokinetic/Pharmacodynamic Determination and Preclinical Pharmacokinetics of the β-Lactamase Inhibitor ETX1317 and Its Orally Available Prodrug ETX0282

[Image: see text] Increasingly resistant Enterobacteriaceae have emerged as a health threat in both hospital and community settings. Infections of the urinary tract, once often treated with oral agents in the community, are requiring increased hospitalization and use of intravenously administered ag...

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Detalles Bibliográficos
Autores principales: O’Donnell, John, Tanudra, Angela, Chen, April, Hines, Daniel, Tommasi, Ruben, Mueller, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297445/
https://www.ncbi.nlm.nih.gov/pubmed/32379415
http://dx.doi.org/10.1021/acsinfecdis.0c00019