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Precursor Lesions of Cholangiocarcinoma: A Clinicopathologic Review
Cholangiocarcinoma (CCA) develops through multistep carcinogenesis. During the past decades, 2 precursors have been proved to evolve to CCA. The 2 main precursor lesions of CCA are biliary intraepithelial neoplasia and intraductal papillary neoplasm of the bile duct. It is an interesting and relativ...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297471/ https://www.ncbi.nlm.nih.gov/pubmed/32596664 http://dx.doi.org/10.1177/2632010X20925045 |
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author | Geramizadeh, Bita |
author_facet | Geramizadeh, Bita |
author_sort | Geramizadeh, Bita |
collection | PubMed |
description | Cholangiocarcinoma (CCA) develops through multistep carcinogenesis. During the past decades, 2 precursors have been proved to evolve to CCA. The 2 main precursor lesions of CCA are biliary intraepithelial neoplasia and intraductal papillary neoplasm of the bile duct. It is an interesting and relatively novel entity for the hepatobiliary surgeons, radiologists, oncologists, and pathologists. It worth being familiar with these 2 entities for better communication between pathologists, oncologists, and surgeons to improve the treatment and follow-up of these lesions, which can definitely decrease their evolvement to CCA as an aggressive, poor prognostic, and life-threatening cancer. In this narrative review, I collected and discussed all published studies about these 2 precursor lesions of CCA including radiologic, clinical, and pathological manifestation. |
format | Online Article Text |
id | pubmed-7297471 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-72974712020-06-25 Precursor Lesions of Cholangiocarcinoma: A Clinicopathologic Review Geramizadeh, Bita Clin Pathol Review Cholangiocarcinoma (CCA) develops through multistep carcinogenesis. During the past decades, 2 precursors have been proved to evolve to CCA. The 2 main precursor lesions of CCA are biliary intraepithelial neoplasia and intraductal papillary neoplasm of the bile duct. It is an interesting and relatively novel entity for the hepatobiliary surgeons, radiologists, oncologists, and pathologists. It worth being familiar with these 2 entities for better communication between pathologists, oncologists, and surgeons to improve the treatment and follow-up of these lesions, which can definitely decrease their evolvement to CCA as an aggressive, poor prognostic, and life-threatening cancer. In this narrative review, I collected and discussed all published studies about these 2 precursor lesions of CCA including radiologic, clinical, and pathological manifestation. SAGE Publications 2020-06-15 /pmc/articles/PMC7297471/ /pubmed/32596664 http://dx.doi.org/10.1177/2632010X20925045 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review Geramizadeh, Bita Precursor Lesions of Cholangiocarcinoma: A Clinicopathologic Review |
title | Precursor Lesions of Cholangiocarcinoma: A Clinicopathologic Review |
title_full | Precursor Lesions of Cholangiocarcinoma: A Clinicopathologic Review |
title_fullStr | Precursor Lesions of Cholangiocarcinoma: A Clinicopathologic Review |
title_full_unstemmed | Precursor Lesions of Cholangiocarcinoma: A Clinicopathologic Review |
title_short | Precursor Lesions of Cholangiocarcinoma: A Clinicopathologic Review |
title_sort | precursor lesions of cholangiocarcinoma: a clinicopathologic review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297471/ https://www.ncbi.nlm.nih.gov/pubmed/32596664 http://dx.doi.org/10.1177/2632010X20925045 |
work_keys_str_mv | AT geramizadehbita precursorlesionsofcholangiocarcinomaaclinicopathologicreview |