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Noscapine Induces Apoptosis in Human Colon Cancer Cells by Regulating Mitochondrial Damage and Warburg Effect via PTEN/PI3K/mTOR Signaling Pathway

BACKGROUND: Noscapine is an opium alkaloid that has recently been shown to potentiate anti-cancer therapeutic effects by inducing apoptosis in various malignant cells without any detectable toxicity. However, the mechanism by which noscapine induces apoptosis in colon cancer cells remains unclear. M...

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Detalles Bibliográficos
Autores principales: Tian, Xia, Liu, Meng, Huang, Xiaodong, Zhu, Qingxi, Liu, Weijie, Chen, Wei, Zou, Yanli, Cai, Yishan, Huang, Shasha, Chen, Aifang, Zhan, Ting, Huang, Min, Chen, Xiaoli, Han, Zheng, Tan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297602/
https://www.ncbi.nlm.nih.gov/pubmed/32606759
http://dx.doi.org/10.2147/OTT.S232137