The deubiquitylase UCHL3 maintains cancer stem-like properties by stabilizing the aryl hydrocarbon receptor

Cancer stem cells (CSCs) exhibit highly aggressive and metastatic features and resistance to chemotherapy and radiotherapy. Aryl hydrocarbon receptor (AhR) expression varies among non-small cell lung cancers (NSCLCs), and the mechanisms that support abnormal AhR expression in CSCs remain elusive. He...

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Detalles Bibliográficos
Autores principales: Ouyang, Lianlian, Yan, Bin, Liu, Yating, Mao, Chao, Wang, Min, Liu, Na, Wang, Zuli, Liu, Shouping, Shi, Ying, Chen, Ling, Wang, Xiang, Cheng, Yan, Cao, Ya, Xiao, Desheng, Zhang, Lingqiang, Liu, Shuang, Tao, Yongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297794/
https://www.ncbi.nlm.nih.gov/pubmed/32546741
http://dx.doi.org/10.1038/s41392-020-0181-3

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