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KLF5 inhibits STAT3 activity and tumor metastasis in prostate cancer by suppressing IGF1 transcription cooperatively with HDAC1

KLF5 is frequently deleted and downregulated in prostate cancer, and recently it has been reported that KLF5 loss is enriched in the aggressive branches of prostate cancer evolution. However, why KLF5 loss is associated with prostate cancer aggressiveness is still not clear. Herein, we analyzed KLF5...

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Detalles Bibliográficos
Autores principales:	Ma, Jian-Bin, Bai, Ji-Yu, Zhang, Hai-Bao, Jia, Jing, Shi, Qi, Yang, Chao, Wang, Xinyang, He, Dalin, Guo, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297795/ https://www.ncbi.nlm.nih.gov/pubmed/32546700 http://dx.doi.org/10.1038/s41419-020-2671-1

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