BGP-15 Protects Mitochondria in Acute, Acetaminophen Overdose Induced Liver Injury

Acetaminophen (APAP) induced hepatotoxicity involves activation of c-Jun amino-terminal kinase (JNK), mitochondrial damage and ER stress. BGP-15, a hydroximic acid derivative, has been reported to have hepatoprotective effects in APAP overdose induced liver damage. Effect of BGP-15 was further inves...

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Detalles Bibliográficos
Autores principales: Sarnyai, Farkas, Szekerczés, Timea, Csala, Miklós, Sümegi, Balázs, Szarka, András, Schaff, Zsuzsa, Mandl, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297855/
https://www.ncbi.nlm.nih.gov/pubmed/31705481
http://dx.doi.org/10.1007/s12253-019-00721-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297855/
https://www.ncbi.nlm.nih.gov/pubmed/31705481
http://dx.doi.org/10.1007/s12253-019-00721-1

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