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Prenatal stress causes intrauterine inflammation and serotonergic dysfunction, and long-term behavioral deficits through microbe- and CCL2-dependent mechanisms

Prenatal stress (PNS) is associated with neuropsychiatric disorders in offspring, including anxiety, depression, and autism spectrum disorders. There is mounting evidence that these behavioral phenotypes have origins in utero. Maternal microbes, inflammation, and serotonergic dysfunction have been i...

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Detalles Bibliográficos
Autores principales: Chen, Helen J., Antonson, Adrienne M., Rajasekera, Therese A., Patterson, Jenna M., Bailey, Michael T., Gur, Tamar L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297973/
https://www.ncbi.nlm.nih.gov/pubmed/32546752
http://dx.doi.org/10.1038/s41398-020-00876-5

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