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Prenatal stress causes intrauterine inflammation and serotonergic dysfunction, and long-term behavioral deficits through microbe- and CCL2-dependent mechanisms
Prenatal stress (PNS) is associated with neuropsychiatric disorders in offspring, including anxiety, depression, and autism spectrum disorders. There is mounting evidence that these behavioral phenotypes have origins in utero. Maternal microbes, inflammation, and serotonergic dysfunction have been i...
Autores principales: | Chen, Helen J., Antonson, Adrienne M., Rajasekera, Therese A., Patterson, Jenna M., Bailey, Michael T., Gur, Tamar L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297973/ https://www.ncbi.nlm.nih.gov/pubmed/32546752 http://dx.doi.org/10.1038/s41398-020-00876-5 |
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