Alzheimer’s disease-related dysregulation of mRNA translation causes key pathological features with ageing

Alzheimer’s disease (AD) is characterised by Aβ and tau pathology as well as synaptic degeneration, which correlates best with cognitive impairment. Previous work suggested that this pathological complexity may result from changes in mRNA translation. Here, we studied whether mRNA translation and it...

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Detalles Bibliográficos
Autores principales: Ghosh, Anshua, Mizuno, Keiko, Tiwari, Sachin S., Proitsi, Petroula, Gomez Perez-Nievas, Beatriz, Glennon, Elizabeth, Martinez-Nunez, Rocio T., Giese, K. Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297996/
https://www.ncbi.nlm.nih.gov/pubmed/32546772
http://dx.doi.org/10.1038/s41398-020-00882-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297996/
https://www.ncbi.nlm.nih.gov/pubmed/32546772
http://dx.doi.org/10.1038/s41398-020-00882-7

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