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Alzheimer’s disease-related dysregulation of mRNA translation causes key pathological features with ageing
Alzheimer’s disease (AD) is characterised by Aβ and tau pathology as well as synaptic degeneration, which correlates best with cognitive impairment. Previous work suggested that this pathological complexity may result from changes in mRNA translation. Here, we studied whether mRNA translation and it...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297996/ https://www.ncbi.nlm.nih.gov/pubmed/32546772 http://dx.doi.org/10.1038/s41398-020-00882-7 |