Hepatic HuR modulates lipid homeostasis in response to high-fat diet

Lipid transport and ATP synthesis are critical for the progression of non-alcoholic fatty liver disease (NAFLD), but the underlying mechanisms are largely unknown. Here, we report that the RNA-binding protein HuR (ELAVL1) forms complexes with NAFLD-relevant transcripts. It associates with intron 24...

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Detalles Bibliográficos
Autores principales: Zhang, Zhuojun, Zong, Chen, Jiang, Mingyang, Hu, Han, Cheng, Xiaolei, Ni, Juhua, Yi, Xia, Jiang, Bin, Tian, Feng, Chang, Ming-Wen, Su, Wen, Zhu, Lijun, Li, Jinfan, Xiang, Xueping, Miao, Congxiu, Gorospe, Myriam, de Cabo, Rafael, Dou, Yali, Ju, Zhenyu, Yang, Jichun, Jiang, Changtao, Yang, Zhongzhou, Wang, Wengong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298042/
https://www.ncbi.nlm.nih.gov/pubmed/32546794
http://dx.doi.org/10.1038/s41467-020-16918-x

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