Thrombotic complications of COVID-19 may reflect an upregulation of endothelial tissue factor expression that is contingent on activation of endosomal NADPH oxidase

The high rate of thrombotic complications associated with COVID-19 seems likely to reflect viral infection of vascular endothelial cells, which express the ACE2 protein that enables SARS-CoV-2 to invade cells. Various proinflammatory stimuli can promote thrombosis by inducing luminal endothelial exp...

Descripción completa

Detalles Bibliográficos
Autores principales: DiNicolantonio, James J, McCarty, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Pulmonary Vascular Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298678/
https://www.ncbi.nlm.nih.gov/pubmed/32532805
http://dx.doi.org/10.1136/openhrt-2020-001337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298678/
https://www.ncbi.nlm.nih.gov/pubmed/32532805
http://dx.doi.org/10.1136/openhrt-2020-001337

Ejemplares similares