Role of DNA methylation in the association of lung function with body mass index: a two-step epigenetic Mendelian randomisation study

BACKGROUND: Low lung function has been associated with increased body mass index (BMI). The aim of this study was to investigate whether the effect of BMI on lung function is mediated by DNA methylation. METHODS: We used individual data from 285,495 participants in four population-based cohorts: the...

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Detalles Bibliográficos
Autores principales: Amaral, André F. S., Imboden, Medea, Wielscher, Matthias, Rezwan, Faisal I., Minelli, Cosetta, Garcia-Aymerich, Judith, Peralta, Gabriela P., Auvinen, Juha, Jeong, Ayoung, Schaffner, Emmanuel, Beckmeyer-Borowko, Anna, Holloway, John W., Jarvelin, Marjo-Riitta, Probst-Hensch, Nicole M., Jarvis, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298775/
https://www.ncbi.nlm.nih.gov/pubmed/32546146
http://dx.doi.org/10.1186/s12890-020-01212-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298775/
https://www.ncbi.nlm.nih.gov/pubmed/32546146
http://dx.doi.org/10.1186/s12890-020-01212-9

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