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Sensitivity, specificity, inclusivity and exclusivity of the updated Aptima Combo 2 assay, which provides detection coverage of the new diagnostic-escape Chlamydia trachomatis variants

BACKGROUND: Four new variants of Chlamydia trachomatis (nvCTs), detected in several countries, cause false-negative or equivocal results using the Aptima Combo 2 assay (AC2; Hologic). We evaluated the clinical sensitivity and specificity, as well as the analytical inclusivity and exclusivity of the...

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Detalles Bibliográficos
Autores principales: Unemo, Magnus, Hansen, Marit, Hadad, Ronza, Puolakkainen, Mirja, Westh, Henrik, Rantakokko-Jalava, Kaisu, Thilesen, Carina, Cole, Michelle J., Boiko, Iryna, Lan, Pham T., Golparian, Daniel, Ito, Shin, Sundqvist, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298785/
https://www.ncbi.nlm.nih.gov/pubmed/32546213
http://dx.doi.org/10.1186/s12879-020-05148-7