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Sensitivity, specificity, inclusivity and exclusivity of the updated Aptima Combo 2 assay, which provides detection coverage of the new diagnostic-escape Chlamydia trachomatis variants
BACKGROUND: Four new variants of Chlamydia trachomatis (nvCTs), detected in several countries, cause false-negative or equivocal results using the Aptima Combo 2 assay (AC2; Hologic). We evaluated the clinical sensitivity and specificity, as well as the analytical inclusivity and exclusivity of the...
Autores principales: | Unemo, Magnus, Hansen, Marit, Hadad, Ronza, Puolakkainen, Mirja, Westh, Henrik, Rantakokko-Jalava, Kaisu, Thilesen, Carina, Cole, Michelle J., Boiko, Iryna, Lan, Pham T., Golparian, Daniel, Ito, Shin, Sundqvist, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298785/ https://www.ncbi.nlm.nih.gov/pubmed/32546213 http://dx.doi.org/10.1186/s12879-020-05148-7 |
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