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Latest Developments in Polypoidal Choroidal Vasculopathy: Epidemiology, Etiology, Diagnosis, and Treatment

Polypoidal choroidal vasculopathy (PCV) is a condition characterized by multiple, recurrent, serosanguineous pigment epithelial detachments, and neurosensory retinal detachments due to abnormal aneurysmal neovascular lesions. It is generally considered as a variant of neovascular age-related macular...

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Autores principales: Chaikitmongkol, Voraporn, Cheung, Chui Ming Gemmy, Koizumi, Hideki, Govindahar, Vishal, Chhablani, Jay, Lai, Timothy Y.Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299215/
https://www.ncbi.nlm.nih.gov/pubmed/32332215
http://dx.doi.org/10.1097/01.APO.0000656992.00746.48
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author Chaikitmongkol, Voraporn
Cheung, Chui Ming Gemmy
Koizumi, Hideki
Govindahar, Vishal
Chhablani, Jay
Lai, Timothy Y.Y.
author_facet Chaikitmongkol, Voraporn
Cheung, Chui Ming Gemmy
Koizumi, Hideki
Govindahar, Vishal
Chhablani, Jay
Lai, Timothy Y.Y.
author_sort Chaikitmongkol, Voraporn
collection PubMed
description Polypoidal choroidal vasculopathy (PCV) is a condition characterized by multiple, recurrent, serosanguineous pigment epithelial detachments, and neurosensory retinal detachments due to abnormal aneurysmal neovascular lesions. It is generally considered as a variant of neovascular age-related macular degeneration, but there are some differences between the clinical presentation, natural history, and treatment response between patients with PCV and typical neovascular age-related macular degeneration patients. Over the past decade, new research and technological advancements have greatly improved our understanding of the PCV disease process and the management of PCV. This review aims to summarize the recent research findings to highlight the epidemiology, pathogenesis, genetics, the application of various diagnostic tools for PCV, and the available treatment options for PCV.
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spelling pubmed-72992152020-06-29 Latest Developments in Polypoidal Choroidal Vasculopathy: Epidemiology, Etiology, Diagnosis, and Treatment Chaikitmongkol, Voraporn Cheung, Chui Ming Gemmy Koizumi, Hideki Govindahar, Vishal Chhablani, Jay Lai, Timothy Y.Y. Asia Pac J Ophthalmol (Phila) Review Article Polypoidal choroidal vasculopathy (PCV) is a condition characterized by multiple, recurrent, serosanguineous pigment epithelial detachments, and neurosensory retinal detachments due to abnormal aneurysmal neovascular lesions. It is generally considered as a variant of neovascular age-related macular degeneration, but there are some differences between the clinical presentation, natural history, and treatment response between patients with PCV and typical neovascular age-related macular degeneration patients. Over the past decade, new research and technological advancements have greatly improved our understanding of the PCV disease process and the management of PCV. This review aims to summarize the recent research findings to highlight the epidemiology, pathogenesis, genetics, the application of various diagnostic tools for PCV, and the available treatment options for PCV. Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong 2020-04-23 /pmc/articles/PMC7299215/ /pubmed/32332215 http://dx.doi.org/10.1097/01.APO.0000656992.00746.48 Text en Copyright © 2020 Asia-Pacific Academy of Ophthalmology. Published by Wolters Kluwer Health, Inc. on behalf of the Asia-Pacific Academy of Ophthalmology. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle Review Article
Chaikitmongkol, Voraporn
Cheung, Chui Ming Gemmy
Koizumi, Hideki
Govindahar, Vishal
Chhablani, Jay
Lai, Timothy Y.Y.
Latest Developments in Polypoidal Choroidal Vasculopathy: Epidemiology, Etiology, Diagnosis, and Treatment
title Latest Developments in Polypoidal Choroidal Vasculopathy: Epidemiology, Etiology, Diagnosis, and Treatment
title_full Latest Developments in Polypoidal Choroidal Vasculopathy: Epidemiology, Etiology, Diagnosis, and Treatment
title_fullStr Latest Developments in Polypoidal Choroidal Vasculopathy: Epidemiology, Etiology, Diagnosis, and Treatment
title_full_unstemmed Latest Developments in Polypoidal Choroidal Vasculopathy: Epidemiology, Etiology, Diagnosis, and Treatment
title_short Latest Developments in Polypoidal Choroidal Vasculopathy: Epidemiology, Etiology, Diagnosis, and Treatment
title_sort latest developments in polypoidal choroidal vasculopathy: epidemiology, etiology, diagnosis, and treatment
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299215/
https://www.ncbi.nlm.nih.gov/pubmed/32332215
http://dx.doi.org/10.1097/01.APO.0000656992.00746.48
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