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Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS

Prokaryotic mechanosensitive (MS) channels open by sensing the physical state of the membrane. As such, lipid-protein interactions represent the defining molecular process underlying mechanotransduction. Here, we describe cryo-electron microscopy (cryo-EM) structures of the E. coli small-conductance...

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Detalles Bibliográficos
Autores principales: Reddy, Bharat, Bavi, Navid, Lu, Allen, Park, Yeonwoo, Perozo, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299334/
https://www.ncbi.nlm.nih.gov/pubmed/31880537
http://dx.doi.org/10.7554/eLife.50486

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