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GDF15: A Hormone Conveying Somatic Distress to the Brain
GDF15 has recently gained scientific and translational prominence with the discovery that its receptor is a GFRAL-RET heterodimer of which GFRAL is expressed solely in the hindbrain. Activation of this receptor results in reduced food intake and loss of body weight and is perceived and recalled by a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299427/ https://www.ncbi.nlm.nih.gov/pubmed/32310257 http://dx.doi.org/10.1210/endrev/bnaa007 |