Not such a small diagnosis: small cell carcinoma of the prostate

Small cell carcinoma (SCC) is an aggressive malignancy most commonly described in the lung. We present a case of a 61-year-old male who presented with a neck swelling and was subsequently found to have metastatic SCC of the prostate. Clinicians should be aware that it metastasizes early. Unlike conv...

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Detalles Bibliográficos
Autores principales: Rauf, Abdul, Smith, Stephanie F, Mukherjee, Rono, Nasir, Nyla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299610/
https://www.ncbi.nlm.nih.gov/pubmed/32582431
http://dx.doi.org/10.1093/jscr/rjaa117
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author Rauf, Abdul
Smith, Stephanie F
Mukherjee, Rono
Nasir, Nyla
author_facet Rauf, Abdul
Smith, Stephanie F
Mukherjee, Rono
Nasir, Nyla
author_sort Rauf, Abdul
collection PubMed
description Small cell carcinoma (SCC) is an aggressive malignancy most commonly described in the lung. We present a case of a 61-year-old male who presented with a neck swelling and was subsequently found to have metastatic SCC of the prostate. Clinicians should be aware that it metastasizes early. Unlike conventional prostate adenocarcinoma, it is not a prostate-specific antigen (PSA) secreting tumor hence serum levels do not correlate with disease severity, and a low PSA reading may give false reassurance. In the future, further studies on genomic typing and novel targeted therapies may achieve better clinical outcomes for patients with this aggressive type of prostate cancer.
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spelling pubmed-72996102020-06-23 Not such a small diagnosis: small cell carcinoma of the prostate Rauf, Abdul Smith, Stephanie F Mukherjee, Rono Nasir, Nyla J Surg Case Rep Case Report Small cell carcinoma (SCC) is an aggressive malignancy most commonly described in the lung. We present a case of a 61-year-old male who presented with a neck swelling and was subsequently found to have metastatic SCC of the prostate. Clinicians should be aware that it metastasizes early. Unlike conventional prostate adenocarcinoma, it is not a prostate-specific antigen (PSA) secreting tumor hence serum levels do not correlate with disease severity, and a low PSA reading may give false reassurance. In the future, further studies on genomic typing and novel targeted therapies may achieve better clinical outcomes for patients with this aggressive type of prostate cancer. Oxford University Press 2020-06-17 /pmc/articles/PMC7299610/ /pubmed/32582431 http://dx.doi.org/10.1093/jscr/rjaa117 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Rauf, Abdul
Smith, Stephanie F
Mukherjee, Rono
Nasir, Nyla
Not such a small diagnosis: small cell carcinoma of the prostate
title Not such a small diagnosis: small cell carcinoma of the prostate
title_full Not such a small diagnosis: small cell carcinoma of the prostate
title_fullStr Not such a small diagnosis: small cell carcinoma of the prostate
title_full_unstemmed Not such a small diagnosis: small cell carcinoma of the prostate
title_short Not such a small diagnosis: small cell carcinoma of the prostate
title_sort not such a small diagnosis: small cell carcinoma of the prostate
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299610/
https://www.ncbi.nlm.nih.gov/pubmed/32582431
http://dx.doi.org/10.1093/jscr/rjaa117
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AT mukherjeerono notsuchasmalldiagnosissmallcellcarcinomaoftheprostate
AT nasirnyla notsuchasmalldiagnosissmallcellcarcinomaoftheprostate

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