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Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells

Transcriptional bursting is the stochastic activation and inactivation of promoters, contributing to cell-to-cell heterogeneity in gene expression. However, the mechanism underlying the regulation of transcriptional bursting kinetics (burst size and frequency) in mammalian cells remains elusive. In...

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Detalles Bibliográficos
Autores principales:	Ochiai, Hiroshi, Hayashi, Tetsutaro, Umeda, Mana, Yoshimura, Mika, Harada, Akihito, Shimizu, Yukiko, Nakano, Kenta, Saitoh, Noriko, Liu, Zhe, Yamamoto, Takashi, Okamura, Tadashi, Ohkawa, Yasuyuki, Kimura, Hiroshi, Nikaido, Itoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299619/ https://www.ncbi.nlm.nih.gov/pubmed/32596448 http://dx.doi.org/10.1126/sciadv.aaz6699

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