Chemokine receptor CXCR3 is required for lethal brain pathology but not pathogen clearance during cryptococcal meningoencephalitis

Cryptococcal meningoencephalitis (CM) is the major cause of infection-related neurological death, typically seen in immunocompromised patients. However, T cell–driven inflammatory response has been increasingly implicated in lethal central nervous system (CNS) immunopathology in human patients and m...

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Detalles Bibliográficos
Autores principales: Xu, Jintao, Neal, Lori M., Ganguly, Anutosh, Kolbe, Jessica L., Hargarten, Jessica C., Elsegeiny, Waleed, Hollingsworth, Christopher, He, Xiumiao, Ivey, Mike, Lopez, Rafael, Zhao, Jessica, Segal, Benjamin, Williamson, Peter R., Olszewski, Michal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299622/
https://www.ncbi.nlm.nih.gov/pubmed/32596454
http://dx.doi.org/10.1126/sciadv.aba2502

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