The proteasome activator PA200 regulates expression of genes involved in cell survival upon selective mitochondrial inhibition in neuroblastoma cells

The conserved Blm10/PA200 activators bind to the proteasome core and facilitate peptide and protein turnover. Blm10/PA200 proteins enhance proteasome peptidase activity and accelerate the degradation of unstructured proteasome substrates. Our knowledge about the exact role of PA200 in diseased cells...

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Detalles Bibliográficos
Autores principales: Douida, Abdennour, Batista, Frank, Robaszkiewicz, Agnieszka, Boto, Pal, Aladdin, Azzam, Szenykiv, Mónika, Czinege, Rita, Virág, László, Tar, Krisztina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299700/
https://www.ncbi.nlm.nih.gov/pubmed/32368861
http://dx.doi.org/10.1111/jcmm.15323

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