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Alternative catalytic residues in the active site of Esco acetyltransferases

Cohesin is a protein complex whose core subunits, Smc1, Smc3, Scc1, and SA1/SA2 form a ring-like structure encircling the DNA. Cohesins play a key role in the expression, repair, and segregation of eukaryotic genomes. Following a catalytic mechanism that is insufficiently understood, Esco1 and Esco2...

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Detalles Bibliográficos
Autores principales:	Ajam, Tahereh, De, Inessa, Petkau, Nikolai, Whelan, Gabriela, Pena, Vladimir, Eichele, Gregor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300003/ https://www.ncbi.nlm.nih.gov/pubmed/32555289 http://dx.doi.org/10.1038/s41598-020-66795-z

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