Cargando…
Fusing α and β subunits of the fungal fatty acid synthase leads to improved production of fatty acids
Most fungal fatty acid synthases assemble from two multidomain subunits, α and β, into a heterododecameric FAS complex. It has been recently shown that the complex assembly occurs in a cotranslational manner and is initiated by an interaction between the termini of α and β subunits. This initial eng...
Autores principales: | Wernig, Florian, Born, Sandra, Boles, Eckhard, Grininger, Martin, Oreb, Mislav |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300031/ https://www.ncbi.nlm.nih.gov/pubmed/32555375 http://dx.doi.org/10.1038/s41598-020-66629-y |
Ejemplares similares
-
De novo biosynthesis of 8-hydroxyoctanoic acid via a medium-chain length specific fatty acid synthase and cytochrome P450 in Saccharomyces cerevisiae
por: Wernig, Florian, et al.
Publicado: (2019) -
An engineered fatty acid synthase combined with a carboxylic acid reductase enables de novo production of 1-octanol in Saccharomyces cerevisiae
por: Henritzi, Sandra, et al.
Publicado: (2018) -
Engineering fungal de novo fatty acid synthesis for short chain fatty acid production
por: Gajewski, Jan, et al.
Publicado: (2017) -
Analysis of the co-translational assembly of the fungal fatty acid synthase (FAS)
por: Fischer, Manuel, et al.
Publicado: (2020) -
Strategies in megasynthase engineering – fatty acid synthases (FAS) as model proteins
por: Fischer, Manuel, et al.
Publicado: (2017)