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Aucuba japonica extract inhibits retinal neovascularization in a mouse model of oxygen‐induced retinopathy, with its bioactive components preventing VEGF‐induced retinal vascular hyperpermeability

Neovascularization in the retina is common pathophysiology of diabetic retinal microvasculopathy and exudative macular degeneration. Our study assessed the inhibitory activity of an ethanol‐based extract of Aucuba japonica (AJE) on abnormal angiogenesis in the retina with a hyperoxia‐induced neovasc...

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Detalles Bibliográficos
Autores principales: Jung, Eunsoo, Jung, Woo Kwon, Park, Su‐Bin, Kim, Hyung Rae, Kim, Junghyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300051/
https://www.ncbi.nlm.nih.gov/pubmed/32566207
http://dx.doi.org/10.1002/fsn3.1590