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WNT and inflammatory signaling distinguish human Fallopian tube epithelial cell populations

Many high-grade serous carcinomas (HGSCs) likely originate in the distal region of the Fallopian tube’s epithelium (TE) before metastasizing to the ovary. Unfortunately, molecular mechanisms promoting malignancy in the distal TE are obfuscated, largely due to limited primary human TE gene expression...

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Detalles Bibliográficos
Autores principales: Rose, Ian M., Bidarimath, Mallikarjun, Webster, Alex, Godwin, Andrew K., Flesken-Nikitin, Andrea, Nikitin, Alexander Yu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300082/
https://www.ncbi.nlm.nih.gov/pubmed/32555344
http://dx.doi.org/10.1038/s41598-020-66556-y

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