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Simulating the human colorectal cancer microenvironment in 3D tumor-stroma co-cultures in vitro and in vivo
The tumor microenvironment (TME) plays a significant role in cancer progression and thus modeling it will advance our understanding of cancer growth dynamics and response to therapies. Most in vitro models are not exposed to intact body physiology, and at the same time, fail to recapitulate the exte...
Autores principales: | Devarasetty, Mahesh, Dominijanni, Anthony, Herberg, Samuel, Shelkey, Ethan, Skardal, Aleksander, Soker, Shay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300090/ https://www.ncbi.nlm.nih.gov/pubmed/32555362 http://dx.doi.org/10.1038/s41598-020-66785-1 |
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