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Simulating the human colorectal cancer microenvironment in 3D tumor-stroma co-cultures in vitro and in vivo

The tumor microenvironment (TME) plays a significant role in cancer progression and thus modeling it will advance our understanding of cancer growth dynamics and response to therapies. Most in vitro models are not exposed to intact body physiology, and at the same time, fail to recapitulate the exte...

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Detalles Bibliográficos
Autores principales: Devarasetty, Mahesh, Dominijanni, Anthony, Herberg, Samuel, Shelkey, Ethan, Skardal, Aleksander, Soker, Shay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300090/
https://www.ncbi.nlm.nih.gov/pubmed/32555362
http://dx.doi.org/10.1038/s41598-020-66785-1

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