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Strategies to Investigate Ubiquitination in Huntington's Disease

Many neurodegenerative disorders including Huntington's Disease are hallmarked by intracellular protein aggregates that are decorated by ubiquitin and different ubiquitin ligases and deubiquitinating enzymes. The protein aggregates observed in Huntington's Disease are caused by a polygluta...

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Detalles Bibliográficos
Autores principales:	Sap, Karen A., Reits, Eric A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300180/ https://www.ncbi.nlm.nih.gov/pubmed/32596207 http://dx.doi.org/10.3389/fchem.2020.00485

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