Initial Dosage Recommendation for Sirolimus in Children With Tuberous Sclerosis Complex

Sirolimus is already used in the treatment of tuberous sclerosis complex (TSC), however, with narrow therapeutic range and considerable inter- and intra-individual pharmacokinetic variability, making it hard to develop an appropriate sirolimus initial dosage regimen, especially in children with TSC....

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Detalles Bibliográficos
Autores principales: Wang, Dong-Dong, Chen, Xiao, Xu, Hong, Li, Zhi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300220/
https://www.ncbi.nlm.nih.gov/pubmed/32595509
http://dx.doi.org/10.3389/fphar.2020.00890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300220/
https://www.ncbi.nlm.nih.gov/pubmed/32595509
http://dx.doi.org/10.3389/fphar.2020.00890

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