STAT3 gain-of-function mutation in a patient with pulmonary Mycobacterium abscessus infection

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) is a transcription factor involved in cellular proliferation, apoptosis, and differentiation. Mutations in the STAT3 gene have been associated with dysregulation of the immune system giving rise to primary immunodeficiency syndro...

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Detalles Bibliográficos
Autores principales: Gonzalez-Mancera, Miguel S., Johnson, Britt, Mirsaeidi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300236/
https://www.ncbi.nlm.nih.gov/pubmed/32577366
http://dx.doi.org/10.1016/j.rmcr.2020.101125

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