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BRIDGE – A Visual Analytics Web Tool for Barley Genebank Genomics

Genebanks harbor a large treasure trove of untapped plant genetic diversity. A growing world population and a changing climate require an increase in the production and development of stress resistant plant cultivars while decreasing the acreage. These requirements for improved plant cultivars can b...

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Autores principales: König, Patrick, Beier, Sebastian, Basterrechea, Martin, Schüler, Danuta, Arend, Daniel, Mascher, Martin, Stein, Nils, Scholz, Uwe, Lange, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300248/
https://www.ncbi.nlm.nih.gov/pubmed/32595658
http://dx.doi.org/10.3389/fpls.2020.00701
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author König, Patrick
Beier, Sebastian
Basterrechea, Martin
Schüler, Danuta
Arend, Daniel
Mascher, Martin
Stein, Nils
Scholz, Uwe
Lange, Matthias
author_facet König, Patrick
Beier, Sebastian
Basterrechea, Martin
Schüler, Danuta
Arend, Daniel
Mascher, Martin
Stein, Nils
Scholz, Uwe
Lange, Matthias
author_sort König, Patrick
collection PubMed
description Genebanks harbor a large treasure trove of untapped plant genetic diversity. A growing world population and a changing climate require an increase in the production and development of stress resistant plant cultivars while decreasing the acreage. These requirements for improved plant cultivars can be supported by the broader exploitation of plant genetic resources (PGR) as inputs for genomics-assisted breeding. To support this process we have developed BRIDGE, a data warehouse and exploratory data analysis tool for genebank genomics of barley (Hordeum vulgare L.). Using efficient technologies for data storage, data transfer and web development, we facilitate access to digital genebank resources of barley by prioritizing the interactive and visual analysis of integrated genotypic and phenotypic data. The underlying data resulted from a barley genebank genomics study cataloging sequence and morphological data of 22,626 barley accessions, mainly from the German Federal ex situ genebank. BRIDGE consists of interactively coupled modules to visualize integrated, curated and quality checked data, such as variation data, results of dimensionality reduction and genome wide association studies (GWAS), phenotyping results, passport data as well as the geographic distribution of germplasm samples. The core component is a manager for custom collections of germplasm. A search module to find and select germplasm by passport and phenotypic attributes is included as well as modules to export genotypic data in gzip-compressed variant call format (VCF) files and phenotypic data in MIAPPE-compliant ISA-Tab files. BRIDGE is accessible at the following URL: https://bridge.ipk-gatersleben.de.
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spelling pubmed-73002482020-06-26 BRIDGE – A Visual Analytics Web Tool for Barley Genebank Genomics König, Patrick Beier, Sebastian Basterrechea, Martin Schüler, Danuta Arend, Daniel Mascher, Martin Stein, Nils Scholz, Uwe Lange, Matthias Front Plant Sci Plant Science Genebanks harbor a large treasure trove of untapped plant genetic diversity. A growing world population and a changing climate require an increase in the production and development of stress resistant plant cultivars while decreasing the acreage. These requirements for improved plant cultivars can be supported by the broader exploitation of plant genetic resources (PGR) as inputs for genomics-assisted breeding. To support this process we have developed BRIDGE, a data warehouse and exploratory data analysis tool for genebank genomics of barley (Hordeum vulgare L.). Using efficient technologies for data storage, data transfer and web development, we facilitate access to digital genebank resources of barley by prioritizing the interactive and visual analysis of integrated genotypic and phenotypic data. The underlying data resulted from a barley genebank genomics study cataloging sequence and morphological data of 22,626 barley accessions, mainly from the German Federal ex situ genebank. BRIDGE consists of interactively coupled modules to visualize integrated, curated and quality checked data, such as variation data, results of dimensionality reduction and genome wide association studies (GWAS), phenotyping results, passport data as well as the geographic distribution of germplasm samples. The core component is a manager for custom collections of germplasm. A search module to find and select germplasm by passport and phenotypic attributes is included as well as modules to export genotypic data in gzip-compressed variant call format (VCF) files and phenotypic data in MIAPPE-compliant ISA-Tab files. BRIDGE is accessible at the following URL: https://bridge.ipk-gatersleben.de. Frontiers Media S.A. 2020-06-11 /pmc/articles/PMC7300248/ /pubmed/32595658 http://dx.doi.org/10.3389/fpls.2020.00701 Text en Copyright © 2020 König, Beier, Basterrechea, Schüler, Arend, Mascher, Stein, Scholz and Lange. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
König, Patrick
Beier, Sebastian
Basterrechea, Martin
Schüler, Danuta
Arend, Daniel
Mascher, Martin
Stein, Nils
Scholz, Uwe
Lange, Matthias
BRIDGE – A Visual Analytics Web Tool for Barley Genebank Genomics
title BRIDGE – A Visual Analytics Web Tool for Barley Genebank Genomics
title_full BRIDGE – A Visual Analytics Web Tool for Barley Genebank Genomics
title_fullStr BRIDGE – A Visual Analytics Web Tool for Barley Genebank Genomics
title_full_unstemmed BRIDGE – A Visual Analytics Web Tool for Barley Genebank Genomics
title_short BRIDGE – A Visual Analytics Web Tool for Barley Genebank Genomics
title_sort bridge – a visual analytics web tool for barley genebank genomics
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300248/
https://www.ncbi.nlm.nih.gov/pubmed/32595658
http://dx.doi.org/10.3389/fpls.2020.00701
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