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Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 To Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution
Before it was molecularly cloned in 1994, acute-phase response factor or signal transducer and activator of transcription (STAT)3 was the focus of intense research into understanding the mammalian response to injury, particularly the acute-phase response. Although known to be essential for liver pro...
Autores principales: | Bharadwaj, Uddalak, Kasembeli, Moses M., Robinson, Prema, Tweardy, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300325/ https://www.ncbi.nlm.nih.gov/pubmed/32198236 http://dx.doi.org/10.1124/pr.119.018440 |
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