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miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway

The adult Leydig cells (ALCs), originated from stem Leydig cells (SLCs), can secrete testosterone which is essential for germ cell development and sexual behavior maintenance. As a synthetic compound, ethane dimethane sulfonate (EDS), a well-known alkylating agent, has been reported to specifically...

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Detalles Bibliográficos
Autores principales:	Cui, Yang, Chen, Rui, Ma, Lin, Yang, Wenjing, Chen, Mingyue, Zhang, Yanghai, Yu, Shuai, Dong, Wuzi, Zeng, Wenxian, Lan, Xianyong, Pan, Chuanying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300349/ https://www.ncbi.nlm.nih.gov/pubmed/32596241 http://dx.doi.org/10.3389/fcell.2020.00448

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