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The Agr-Like Quorum-Sensing System Is Important for Clostridium perfringens Type A Strain ATCC 3624 To Cause Gas Gangrene in a Mouse Model

Clostridium perfringens type A is involved in gas gangrene in humans and animals. Following a traumatic injury, rapid bacterial proliferation and exotoxin production result in severe myonecrosis. C. perfringens alpha toxin (CPA) and perfringolysin (PFO) are the main virulence factors responsible for...

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Detalles Bibliográficos
Autores principales:	Navarro, Mauricio A., Li, Jihong, Beingesser, Juliann, McClane, Bruce A., Uzal, Francisco A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300355/ https://www.ncbi.nlm.nih.gov/pubmed/32554714 http://dx.doi.org/10.1128/mSphere.00500-20

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