Liver-Specific siRNA-Mediated Stat3 or C3 Knockdown Improves the Outcome of Experimental Autoimmune Myocarditis

Myocarditis can lead to autoimmune disease, dilated cardiomyopathy, and heart failure, which is modeled in the mouse by cardiac myosin immunization (experimental autoimmune myocarditis [EAM]). Signal transducer and activator of transcription 3 (STAT3) systemic inhibition exerts both preventive and t...

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Detalles Bibliográficos
Autores principales: Avalle, Lidia, Marino, Francesca, Camporeale, Annalisa, Guglielmi, Chiara, Viavattene, Daniele, Bandini, Silvio, Conti, Laura, Cimino, James, Forni, Marco, Zanini, Cristina, Ghigo, Alessandra, Bogorad, Roman L., Cavallo, Federica, Provero, Paolo, Koteliansky, Victor, Poli, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301178/
https://www.ncbi.nlm.nih.gov/pubmed/32577433
http://dx.doi.org/10.1016/j.omtm.2020.05.023

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