Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds

Current methods to replace damaged upper airway epithelium with exogenous cells are limited. Existing strategies use grafts that lack mucociliary function, leading to infection and the retention of secretions and keratin debris. Strategies that regenerate airway epithelium with mucociliary function...

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Detalles Bibliográficos
Autores principales: Hamilton, Nick J.I., Lee, Dani Do Hyang, Gowers, Kate H.C., Butler, Colin R., Maughan, Elizabeth F., Jevans, Benjamin, Orr, Jessica C., McCann, Conor J., Burns, Alan J., MacNeil, Sheila, Birchall, Martin A., O'Callaghan, Christopher, Hynds, Robert E., Janes, Sam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301290/
https://www.ncbi.nlm.nih.gov/pubmed/32444408
http://dx.doi.org/10.1183/13993003.01200-2019

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