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Individual and joint contributions of genetic and methylation risk scores for enhancing lung cancer risk stratification: data from a population-based cohort in Germany

BACKGROUND: Risk stratification for lung cancer (LC) screening is so far mostly based on smoking history. This study aimed to assess if and to what extent such risk stratification could be enhanced by additional consideration of genetic risk scores (GRSs) and epigenetic risk scores defined by DNA me...

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Detalles Bibliográficos
Autores principales: Yu, Haixin, Raut, Janhavi R., Schöttker, Ben, Holleczek, Bernd, Zhang, Yan, Brenner, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301507/
https://www.ncbi.nlm.nih.gov/pubmed/32552915
http://dx.doi.org/10.1186/s13148-020-00872-y

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