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Interference chromatography: a novel approach to optimizing chromatographic selectivity and separation performance for virus purification
BACKGROUND: Oncolytic viruses are playing an increasingly important role in cancer immunotherapy applications. Given the preclinical and clinical efficacy of these virus-based therapeutics, there is a need for fast, simple, and inexpensive downstream processing methodologies to purify biologically a...
Autores principales: | Santry, Lisa A., Jacquemart, Renaud, Vandersluis, Melissa, Zhao, Mochao, Domm, Jake M., McAusland, Thomas M., Shang, Xiaojiao, Major, Pierre M., Stout, James G., Wootton, Sarah K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301511/ https://www.ncbi.nlm.nih.gov/pubmed/32552807 http://dx.doi.org/10.1186/s12896-020-00627-w |
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