Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient

SARS-CoV-2 caused a major outbreak of severe pneumonia (COVID-19) in humans. Viral RNA was detected in multiple organs in COVID-19 patients. However, infectious SARS-CoV-2 was only isolated from respiratory specimens. Here, infectious SARS-CoV-2 was successfully isolated from urine of a COVID-19 pat...

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Detalles Bibliográficos
Autores principales: Sun, Jing, Zhu, Airu, Li, Heying, Zheng, Kui, Zhuang, Zhen, Chen, Zhao, Shi, Yongxia, Zhang, Zhaoyong, Chen, Si-bei, Liu, Xuesong, Dai, Jun, Li, Xiaobo, Huang, Shuxiang, Huang, Xiaofang, Luo, Ling, Wen, Liyan, Zhuo, Jianfen, Li, Yuming, Wang, Yanqun, Zhang, Lu, Zhang, Yanjun, Li, Fang, Feng, Liqiang, Chen, Xinwen, Zhong, Nanshan, Yang, Zifeng, Huang, Jicheng, Zhao, Jincun, Li, Yi-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301718/
https://www.ncbi.nlm.nih.gov/pubmed/32342724
http://dx.doi.org/10.1080/22221751.2020.1760144
Descripción
Sumario:SARS-CoV-2 caused a major outbreak of severe pneumonia (COVID-19) in humans. Viral RNA was detected in multiple organs in COVID-19 patients. However, infectious SARS-CoV-2 was only isolated from respiratory specimens. Here, infectious SARS-CoV-2 was successfully isolated from urine of a COVID-19 patient. The virus isolated could infect new susceptible cells and was recognized by its’ own patient sera. Appropriate precautions should be taken to avoid transmission from urine.

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