Activation of the renin-angiotensin-aldosterone system is associated with Acute Kidney Injury in COVID-19

The pathophysiology of acute kidney injury (AKI) in COVID-19 patients is still poorly understood. SARS-CoV-2 has been suggested to modulate the renin-angiotensin-aldosterone system (RAAS). In this series of COVID-19 critically ill patients, we report evidence of activation of the RAAS in COVID-19 pa...

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Autores principales: Dudoignon, Emmanuel, Moreno, Nabila, Deniau, Benjamin, Coutrot, Maxime, Longer, Romain, Amiot, Quentin, Mebazaa, Alexandre, Pirracchio, Romain, Depret, François, Legrand, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Société française d'anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301818/
https://www.ncbi.nlm.nih.gov/pubmed/32565254
http://dx.doi.org/10.1016/j.accpm.2020.06.006
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author Dudoignon, Emmanuel
Moreno, Nabila
Deniau, Benjamin
Coutrot, Maxime
Longer, Romain
Amiot, Quentin
Mebazaa, Alexandre
Pirracchio, Romain
Depret, François
Legrand, Matthieu
author_facet Dudoignon, Emmanuel
Moreno, Nabila
Deniau, Benjamin
Coutrot, Maxime
Longer, Romain
Amiot, Quentin
Mebazaa, Alexandre
Pirracchio, Romain
Depret, François
Legrand, Matthieu
author_sort Dudoignon, Emmanuel
collection PubMed
description The pathophysiology of acute kidney injury (AKI) in COVID-19 patients is still poorly understood. SARS-CoV-2 has been suggested to modulate the renin-angiotensin-aldosterone system (RAAS). In this series of COVID-19 critically ill patients, we report evidence of activation of the RAAS in COVID-19 patients with AKI.
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spelling pubmed-73018182020-06-18 Activation of the renin-angiotensin-aldosterone system is associated with Acute Kidney Injury in COVID-19 Dudoignon, Emmanuel Moreno, Nabila Deniau, Benjamin Coutrot, Maxime Longer, Romain Amiot, Quentin Mebazaa, Alexandre Pirracchio, Romain Depret, François Legrand, Matthieu Anaesth Crit Care Pain Med Article The pathophysiology of acute kidney injury (AKI) in COVID-19 patients is still poorly understood. SARS-CoV-2 has been suggested to modulate the renin-angiotensin-aldosterone system (RAAS). In this series of COVID-19 critically ill patients, we report evidence of activation of the RAAS in COVID-19 patients with AKI. Société française d'anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. 2020-08 2020-06-18 /pmc/articles/PMC7301818/ /pubmed/32565254 http://dx.doi.org/10.1016/j.accpm.2020.06.006 Text en © 2020 Société française d'anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Dudoignon, Emmanuel
Moreno, Nabila
Deniau, Benjamin
Coutrot, Maxime
Longer, Romain
Amiot, Quentin
Mebazaa, Alexandre
Pirracchio, Romain
Depret, François
Legrand, Matthieu
Activation of the renin-angiotensin-aldosterone system is associated with Acute Kidney Injury in COVID-19
title Activation of the renin-angiotensin-aldosterone system is associated with Acute Kidney Injury in COVID-19
title_full Activation of the renin-angiotensin-aldosterone system is associated with Acute Kidney Injury in COVID-19
title_fullStr Activation of the renin-angiotensin-aldosterone system is associated with Acute Kidney Injury in COVID-19
title_full_unstemmed Activation of the renin-angiotensin-aldosterone system is associated with Acute Kidney Injury in COVID-19
title_short Activation of the renin-angiotensin-aldosterone system is associated with Acute Kidney Injury in COVID-19
title_sort activation of the renin-angiotensin-aldosterone system is associated with acute kidney injury in covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301818/
https://www.ncbi.nlm.nih.gov/pubmed/32565254
http://dx.doi.org/10.1016/j.accpm.2020.06.006
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