Vaccines for COVID-19: The current state of play

There is a strong consensus globally that a COVID-19 vaccine is likely the most effective approach to sustainably controlling the COVID-19 pandemic. An unprecedented research effort and global coordination has resulted in a rapid development of vaccine candidates and initiation of trials. Here, we r...

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Detalles Bibliográficos
Autores principales: Koirala, Archana, Joo, Ye Jin, Khatami, Ameneh, Chiu, Clayton, Britton, Philip N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301825/
https://www.ncbi.nlm.nih.gov/pubmed/32653463
http://dx.doi.org/10.1016/j.prrv.2020.06.010
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author Koirala, Archana
Joo, Ye Jin
Khatami, Ameneh
Chiu, Clayton
Britton, Philip N.
author_facet Koirala, Archana
Joo, Ye Jin
Khatami, Ameneh
Chiu, Clayton
Britton, Philip N.
author_sort Koirala, Archana
collection PubMed
description There is a strong consensus globally that a COVID-19 vaccine is likely the most effective approach to sustainably controlling the COVID-19 pandemic. An unprecedented research effort and global coordination has resulted in a rapid development of vaccine candidates and initiation of trials. Here, we review vaccine types, and progress with 10 vaccine candidates against SARS-CoV-2 – the virus that causes COVID-19 – currently undergoing early phase human trials. We also consider the many challenges of developing and deploying a new vaccine on a global scale, and recommend caution with respect to our expectations of the timeline that may be ahead.
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spelling pubmed-73018252020-06-18 Vaccines for COVID-19: The current state of play Koirala, Archana Joo, Ye Jin Khatami, Ameneh Chiu, Clayton Britton, Philip N. Paediatr Respir Rev Review There is a strong consensus globally that a COVID-19 vaccine is likely the most effective approach to sustainably controlling the COVID-19 pandemic. An unprecedented research effort and global coordination has resulted in a rapid development of vaccine candidates and initiation of trials. Here, we review vaccine types, and progress with 10 vaccine candidates against SARS-CoV-2 – the virus that causes COVID-19 – currently undergoing early phase human trials. We also consider the many challenges of developing and deploying a new vaccine on a global scale, and recommend caution with respect to our expectations of the timeline that may be ahead. Elsevier Ltd. 2020-09 2020-06-18 /pmc/articles/PMC7301825/ /pubmed/32653463 http://dx.doi.org/10.1016/j.prrv.2020.06.010 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Koirala, Archana
Joo, Ye Jin
Khatami, Ameneh
Chiu, Clayton
Britton, Philip N.
Vaccines for COVID-19: The current state of play
title Vaccines for COVID-19: The current state of play
title_full Vaccines for COVID-19: The current state of play
title_fullStr Vaccines for COVID-19: The current state of play
title_full_unstemmed Vaccines for COVID-19: The current state of play
title_short Vaccines for COVID-19: The current state of play
title_sort vaccines for covid-19: the current state of play
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301825/
https://www.ncbi.nlm.nih.gov/pubmed/32653463
http://dx.doi.org/10.1016/j.prrv.2020.06.010
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