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Inhibition of porcine epidemic diarrhea virus (PEDV) replication by A77 1726 through targeting JAK and Src tyrosine kinases

Porcine epidemic diarrhea (PED) virus (PEDV) is a coronavirus that primarily infects porcine intestinal epithelial cells and causes severe diarrhea and high fatality in piglets. A77 1726 is the active metabolite of leflunomide, a clinically approved anti-rheumatoid arthritis (RA) drug. A77 1726 inhi...

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Detalles Bibliográficos
Autores principales:	Li, Xiaomei, Sun, Jing, Prinz, Richard A., Liu, Xiufan, Xu, Xiulong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301827/ https://www.ncbi.nlm.nih.gov/pubmed/32829915 http://dx.doi.org/10.1016/j.virol.2020.06.009

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