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Evaluation of the high definition field of view option of a large-bore computed tomography scanner for radiation therapy simulation

BACKGROUND AND PURPOSE: Computed tomography (CT) scanning is the basis for radiation treatment planning, but the 50-cm standard scanning field of view (sFOV) may be too small for imaging larger patients. We evaluated the 65-cm high-definition (HD) FOV of a large-bore CT scanner for CT number accurac...

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Autores principales: Wu, Richard Y., Williamson, Tyler D., Sahoo, Narayan, Nguyen, Trang, Ikner, Shane M., Liu, Amy Y., Wisdom, Paul G., Lii, MingFu, Hunter, Rachel A., Alvarez, Paola E., Gunn, G. Brandon, Frank, Steven J., Hojo, Yoshifumi, Zhu, X. Ronald, Gillin, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302052/
https://www.ncbi.nlm.nih.gov/pubmed/32551371
http://dx.doi.org/10.1016/j.phro.2020.03.004
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author Wu, Richard Y.
Williamson, Tyler D.
Sahoo, Narayan
Nguyen, Trang
Ikner, Shane M.
Liu, Amy Y.
Wisdom, Paul G.
Lii, MingFu
Hunter, Rachel A.
Alvarez, Paola E.
Gunn, G. Brandon
Frank, Steven J.
Hojo, Yoshifumi
Zhu, X. Ronald
Gillin, Michael T.
author_facet Wu, Richard Y.
Williamson, Tyler D.
Sahoo, Narayan
Nguyen, Trang
Ikner, Shane M.
Liu, Amy Y.
Wisdom, Paul G.
Lii, MingFu
Hunter, Rachel A.
Alvarez, Paola E.
Gunn, G. Brandon
Frank, Steven J.
Hojo, Yoshifumi
Zhu, X. Ronald
Gillin, Michael T.
author_sort Wu, Richard Y.
collection PubMed
description BACKGROUND AND PURPOSE: Computed tomography (CT) scanning is the basis for radiation treatment planning, but the 50-cm standard scanning field of view (sFOV) may be too small for imaging larger patients. We evaluated the 65-cm high-definition (HD) FOV of a large-bore CT scanner for CT number accuracy, geometric distortion, image quality degradation, and dosimetric accuracy of photon treatment plans. MATERIALS AND METHODS: CT number accuracy was tested by placing two 16-cm acrylic phantoms on either side of a 40-cm phantom to simulate a large patient extending beyond the 50-cm-diameter standard scanning FOV. Dosimetric accuracy was tested using anthropomorphic pelvis and thorax phantoms, with additional acrylic body parts on either side of the phantoms. Two volumetric modulated arc therapy beams (a 15-MV and a 6-MV) were used to cover the planning target volumes. Two-dimensional dose distributions were evaluated with GAFChromic film and point dose accuracy was checked with multiple thermoluminescent dosimeter (TLD) capsules placed in the phantoms. Image quality was tested by placing an American College of Radiology accreditation phantom inside the 40-cm phantom. RESULTS: The HD FOV showed substantial changes in CT numbers, with differences of 314 HU–725 HU at different density levels. The volume of the body parts extending into the HD FOV was distorted. However, TLD-reported doses for all PTVs agreed within ±3%. Dose agreement in organs at risk were within the passing criteria, and the gamma index pass rate was >97%. Image quality was degraded. CONCLUSIONS: The HD FOV option is adequate for RT simulation and met accreditation standards, although care should be taken during contouring because of reduced image quality.
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spelling pubmed-73020522020-06-18 Evaluation of the high definition field of view option of a large-bore computed tomography scanner for radiation therapy simulation Wu, Richard Y. Williamson, Tyler D. Sahoo, Narayan Nguyen, Trang Ikner, Shane M. Liu, Amy Y. Wisdom, Paul G. Lii, MingFu Hunter, Rachel A. Alvarez, Paola E. Gunn, G. Brandon Frank, Steven J. Hojo, Yoshifumi Zhu, X. Ronald Gillin, Michael T. Phys Imaging Radiat Oncol Original Research Article BACKGROUND AND PURPOSE: Computed tomography (CT) scanning is the basis for radiation treatment planning, but the 50-cm standard scanning field of view (sFOV) may be too small for imaging larger patients. We evaluated the 65-cm high-definition (HD) FOV of a large-bore CT scanner for CT number accuracy, geometric distortion, image quality degradation, and dosimetric accuracy of photon treatment plans. MATERIALS AND METHODS: CT number accuracy was tested by placing two 16-cm acrylic phantoms on either side of a 40-cm phantom to simulate a large patient extending beyond the 50-cm-diameter standard scanning FOV. Dosimetric accuracy was tested using anthropomorphic pelvis and thorax phantoms, with additional acrylic body parts on either side of the phantoms. Two volumetric modulated arc therapy beams (a 15-MV and a 6-MV) were used to cover the planning target volumes. Two-dimensional dose distributions were evaluated with GAFChromic film and point dose accuracy was checked with multiple thermoluminescent dosimeter (TLD) capsules placed in the phantoms. Image quality was tested by placing an American College of Radiology accreditation phantom inside the 40-cm phantom. RESULTS: The HD FOV showed substantial changes in CT numbers, with differences of 314 HU–725 HU at different density levels. The volume of the body parts extending into the HD FOV was distorted. However, TLD-reported doses for all PTVs agreed within ±3%. Dose agreement in organs at risk were within the passing criteria, and the gamma index pass rate was >97%. Image quality was degraded. CONCLUSIONS: The HD FOV option is adequate for RT simulation and met accreditation standards, although care should be taken during contouring because of reduced image quality. Elsevier 2020-03-26 /pmc/articles/PMC7302052/ /pubmed/32551371 http://dx.doi.org/10.1016/j.phro.2020.03.004 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Research Article
Wu, Richard Y.
Williamson, Tyler D.
Sahoo, Narayan
Nguyen, Trang
Ikner, Shane M.
Liu, Amy Y.
Wisdom, Paul G.
Lii, MingFu
Hunter, Rachel A.
Alvarez, Paola E.
Gunn, G. Brandon
Frank, Steven J.
Hojo, Yoshifumi
Zhu, X. Ronald
Gillin, Michael T.
Evaluation of the high definition field of view option of a large-bore computed tomography scanner for radiation therapy simulation
title Evaluation of the high definition field of view option of a large-bore computed tomography scanner for radiation therapy simulation
title_full Evaluation of the high definition field of view option of a large-bore computed tomography scanner for radiation therapy simulation
title_fullStr Evaluation of the high definition field of view option of a large-bore computed tomography scanner for radiation therapy simulation
title_full_unstemmed Evaluation of the high definition field of view option of a large-bore computed tomography scanner for radiation therapy simulation
title_short Evaluation of the high definition field of view option of a large-bore computed tomography scanner for radiation therapy simulation
title_sort evaluation of the high definition field of view option of a large-bore computed tomography scanner for radiation therapy simulation
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302052/
https://www.ncbi.nlm.nih.gov/pubmed/32551371
http://dx.doi.org/10.1016/j.phro.2020.03.004
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