A novel hotspot and rare somatic mutation p.A138V, at TP53 is associated with poor survival of pancreatic ductal and periampullary adenocarcinoma patients

BACKGROUND: Pancreatic Ductal Adenocarcinoma (PDAC) is a cancer of the exocrine pancreas and 5-year survival rates remain constant at 7%. Along with PDAC, Periampullary Adenocarcinoma (PAC) accounts for 0.5–2% of all gastrointestinal malignancies. Genomic observations were well concluded for PDAC an...

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Detalles Bibliográficos
Autores principales: Saha, Gourab, Singh, Richa, Mandal, Argha, Das, Subrata, Chattopadhyay, Esita, Panja, Prasun, Roy, Paromita, DeSarkar, Navonil, Gulati, Sumit, Ghatak, Supriyo, Ghosh, Shibajyoti, Banerjee, Sudeep, Roy, Bidyut, Ghosh, Saurabh, Chaudhuri, Dipankar, Arora, Neeraj, Biswas, Nidhan K., Sikdar, Nilabja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302128/
https://www.ncbi.nlm.nih.gov/pubmed/32552660
http://dx.doi.org/10.1186/s10020-020-00183-1

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