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The tumour microenvironment of the upper and lower gastrointestinal tract differentially influences dendritic cell maturation

BACKGROUND: Only 10–30% of oesophageal and rectal adenocarcinoma patients treated with neoadjuvant chemoradiotherapy have a complete pathological response. Inflammatory and angiogenic mediators in the tumour microenvironment (TME) may enable evasion of anti-tumour immune responses. METHODS: The TME...

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Detalles Bibliográficos
Autores principales:	Morrissey, Maria E., Byrne, Róisín, Nulty, Celina, McCabe, Niamh H., Lynam-Lennon, Niamh, Butler, Clare T., Kennedy, Susan, O’Toole, Dermot, Larkin, John, McCormick, Paul, Mehigan, Brian, Cathcart, Mary-Clare, Lysaght, Joanne, Reynolds, John V., Ryan, Elizabeth J., Dunne, Margaret R., O’Sullivan, Jacintha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302160/ https://www.ncbi.nlm.nih.gov/pubmed/32552799 http://dx.doi.org/10.1186/s12885-020-07012-y

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