Novel venom-based peptides (P13 and its derivative—M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways

BACKGROUND: In our previous study, a venom-based peptide named Gonearrestide (also named P13) was identified and demonstrated with an effective inhibition in the proliferation of colon cancer cells. In this study, we explored if P13 and its potent mutant M6 could promote the proliferation of human e...

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Detalles Bibliográficos
Autores principales: Ma, Rui, Ren, Zhili, Li, Bin, Siu, Shirley W. I., Chen, Guokai, Kwok, Hang Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302175/
https://www.ncbi.nlm.nih.gov/pubmed/32552810
http://dx.doi.org/10.1186/s13287-020-01766-9

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